Meredith Kercher may have met her killer at a party, police believe
Three people are being questioned by Italian police over the murder of the British student Meredith Kercher.
Miss Kercher, 21, from Coulsdon, south London, is thought to have been stabbed with a pocket knife in Perugia, Italy, where she was due to study for a year.
The BBC's Christian Fraser said two men and one woman were being questioned in what was a "significant development".
He added that Miss Kercher's friend and fellow student, Sophie Purton, had been refused permission to leave Italy.
Italian police are due to hold a press conference later.
Earlier, officers suggested that more than one person may have been involved in Miss Kercher's death.
Her body was found on Friday in the bedroom of her apartment.
She was partially-clothed and under a duvet.
Nicola Miriano, the investigating magistrate, told reporters that Miss Kercher died as a result of "a violent action by an unidentified person or persons".
Luca Lalli, the medical examiner, said there was evidence that she had taken part in sexual activity before her death, but did not confirm reports that she had been raped.
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